I always thought it would be fun to own one of these Erlewine Lazers as most notably played by Johnny Winter.
I think Johnny tunes his down a whole step to D to produce his signature Texas Blues sound. To see what I mean, check out this performance of Johnny playing the Erlewine on his rendition of "Rock Me Baby".
http://www.youtube.com/watch?v=eBcNOp0EZBc